Exercise & Chemotherapy-Induced Neuropathy Podcast

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating neurological side-effect of numerous cancer therapies included in breast, colorectal, prostate, gynaecological and haematological cancer treatments. CIPN is common and can occur in up to three-quarters of patients ranging from mild to severe symptoms, with severe symptoms potentially leading to reduced treatment doses. The main symptoms of CIPN include tingling and numbness, presenting in the hands and feet, which can be accompanied with altered sensation and pain. CIPN can occur during treatment and generally resolves within 6-12 months post-treatment. However, for some patients, symptoms present after cessation of treatment and among a smaller proportion CIPN symptoms may be permanent. 

CIPN can also contribute to functional deficits, including changes in gait, reduced stability and balance issues. Considering many patients receiving cancer treatment may already be a falls risk due to being older, reduced feet sensation and impaired mobility impairing their balance is a critical problem. CIPN can impair fine motor skills and is a significant cause of reduced quality of life. There are no preventative or treatment agents to treat CIPN, however exercise has been suggested as a potential intervention to manage the functional deficits associated with CIPN. 

This is a recording of an ESSA webinar presented on 20 August, 2021. 

Presented by Dr David Mizrahi BExPhys, BSc, PhD, MESSA, AEP

Dr David Mizrahi is an Accredited Exercise Physiologist who specialises in 'exercise-oncology' research. David completed his PhD at the University of New South Wales and Sydney Children’s Hospital in childhood cancer, and also completed a MSc investigating ovarian cancer. David is currently a Clinical Research Officer at the In Focus research group at UNSW investigating chemotherapy-induced peripheral neuropathy and from later 2021 will be time abroad as a Fulbright Scholar investigating exercise for children's cancers with St. Jude Children’s Research Hospital.

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