Vascular Ageing

Vascular Ageing

Vascular Ageing

Vascular ageing refers to the age-related deterioration in vascular structure and function and is accelerated in the presence of cardiovascular risk factors. While age-related arterial damage typically appears in the fifth decade of life, there is wide variability between individuals, with some displaying “early” vascular ageing. This has led to the concept that vascular age, as opposed to chronological age, may be better related to the prognosis of cardiovascular disease (CVD). Arterial stiffness is an important component of vascular ageing and is related to elevated CVD risk, independently of traditional cardiovascular risk factors. Importantly, arterial stiffening limits the buffering capacity of the large elastic arteries, which is hypothesised to expose the microvasculature of target organs to increased pulsatile stress. Thus, arterial stiffness per se may be a mechanism inducing cardiac, renal and brain microcirculatory damage, favouring CVD events. As such, arterial stiffness is emerging as an appealing therapeutic target.

This online activity will cover the pathophysiolgy and prognostic importance of early vascular ageing, what vascular ageing adds to established biomarkers in the clinic, who benefits from the measurement of vascular ageing, why some people display early vascular ageing and how lifestyle changes (in particular exercise) can modify or delay early vascular ageing. 

This is a recording of an ESSA webinar presented on 7 October 2020. 

Presented by Dr Rachel Climie, PhD

Rachel is an exercise physiologist, Heart Foundation postdoctoral research fellow and the Heart Foundation Paul Korner awardee for 2020. She completed her PhD at the Menzies Institute for Medical Research and 2 years postdoctoral research studying cardiovascular epidemiology and arterial mechanics at Paris Research Center Cardiovasculaire (PARCC), France, where she is an Honorary Fellow. The 48 peer-review publications arising from her PhD and postdoctoral research have consistently been published in top tier hypertension/exercise physiology journals including JAMA, JAMA Cardiology, European Heart Journal, Diabetes Care, British Journal of Sports Medicine and Hypertension. Rachel’s research focusses on the ageing of the blood vessels (vascular ageing), the consequences of early vascular ageing (such as in patients with diabetes or cancer) and how exercise can be used to prevent or delay this. In collaboration with her European colleagues, Rachel was recently awarded a European Collaboration in Science and Technology Action grant (VascAgeNet, $1M) to translate vascular ageing research into clinical practice. Rachel is the lead of the Education and Dissemination working group of VascAgeNet. Rachel is also the public engagement representative on the High Blood Pressure Research Council of Australia (HBPRCA) Executive Committee, a member of the Australian Cardiovascular Alliance Emerging Leaders Committee and founding member of the European ARTERY Society Young Investigator Committee. 

Rates per person

ESSA Member
ESSA Student Member
Student Non-Member
ESSA Member PD+   Complimentary
Non-Member PD+    Complimentary
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Access to Online Activity

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Target Audience

Any Accredited Exercise Scientist and/or Accredited Exercise Physiologist


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